Qala

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Very cool zombie survival game. Shoot through a never ending onslaught of zombies in 5 different levels with 8 different weapons that upgrade.

1. Smoking can shorten your penis by as much as a centimeter. Erections are all about good bloodflow, and lighting up calcifies blood vessels, stifling erectile circulation. So even if you don't care all that much about your lungs or dying young, spare the li'l guy.

2. Doctors can now grow skin for burn victims using the foreskins of circumcised infants. One foreskin can produce 23,000 square meters, which would be enough to tarp every Major League infield with human flesh.

3. An enlarged prostate gland can cause both erectile dysfunction and premature ejaculation. If you have an unexplained case of either, your doctor's looking forward to checking your prostate. Even if you're not.

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Yes, you. You control the Information Age. Welcome to your world.

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In a discovery that has stunned even those behind it, scientists at a Toronto hospital say they have proof the body's nervous system helps trigger diabetes, opening the door to a potential near-cure of the disease that affects millions of Canadians.

Diabetic mice became healthy virtually overnight after researchers injected a substance to counteract the effect of malfunctioning pain neurons in the pancreas.

"I couldn't believe it," said Dr. Michael Salter, a pain expert at the Hospital for Sick Children and one of the scientists. "Mice with diabetes suddenly didn't have diabetes any more."

The researchers caution they have yet to confirm their findings in people, but say they expect results from human studies within a year or so. Any treatment that may emerge to help at least some patients would likely be years away from hitting the market.

But the excitement of the team from Sick Kids, whose work is being published today in the journal Cell, is almost palpable.

"I've never seen anything like it," said Dr. Hans Michael Dosch, an immunologist at the hospital and a leader of the studies. "In my career, this is unique."

Their conclusions upset conventional wisdom that Type 1 diabetes, the most serious form of the illness that typically first appears in childhood, was solely caused by auto-immune responses -- the body's immune system turning on itself.

They also conclude that there are far more similarities than previously thought between Type 1 and Type 2 diabetes, and that nerves likely play a role in other chronic inflammatory conditions, such as asthma and Crohn's disease.

The "paradigm-changing" study opens "a novel, exciting door to address one of the diseases with large societal impact," said Dr. Christian Stohler, a leading U.S. pain specialist and dean of dentistry at the University of Maryland, who has reviewed the work.

"The treatment and diagnosis of neuropathic diseases is poised to take a dramatic leap forward because of the impressive research."

About two million Canadians suffer from diabetes, 10% of them with Type 1, contributing to 41,000 deaths a year.

Insulin replacement therapy is the only treatment of Type 1, and cannot prevent many of the side effects, from heart attacks to kidney failure.

In Type 1 diabetes, the pancreas does not produce enough insulin to shift glucose into the cells that need it. In Type 2 diabetes, the insulin that is produced is not used effectively -- something called insulin resistance -- also resulting in poor absorption of glucose.

The problems stem partly from inflammation -- and eventual death -- of insulin-producing islet cells in the pancreas.

Dr. Dosch had concluded in a 1999 paper that there were surprising similarities between diabetes and multiple sclerosis, a central nervous system disease. His interest was also piqued by the presence around the insulin-producing islets of an "enormous" number of nerves, pain neurons primarily used to signal the brain that tissue has been damaged.

Suspecting a link between the nerves and diabetes, he and Dr. Salter used an old experimental trick -- injecting capsaicin, the active ingredient in hot chili peppers, to kill the pancreatic sensory nerves in mice that had an equivalent of Type 1 diabetes.

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Tilt

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Hunger makes the best sauce, goes the maxim. According to researchers at Yale Medical School, it may make quadratic equations and Kant’s categorical imperative go down easier too. The stimulation of hunger, the researchers announced in the March issue of Nature Neuroscience, causes mice to take in information more quickly, and to retain it better — basically, it makes them smarter. And that’s very likely to be true for humans as well.

A team led by Tamas Horvath, chairman of Yale’s comparative medicine program, had been analyzing the pathways followed in mouse brains by ghrelin, a hormone produced by the stomach lining, when the stomach is empty. To the scientists’ surprise, they found that ghrelin was binding to cells not just in the primitive part of the brain that registers hunger (the hypothalamus) but also in the region that plays a role in learning, memory and spatial analysis (the hippocampus).

The researchers then put mice injected with ghrelin and control mice through a maze and other intelligence tests. In each case, the biochemically “hungry” mice — mice infused with ghrelin — performed notably better than those with normal levels of the hormone. The finding was startling, but “it makes sense,” Horvath says. “When you are hungry, you need to focus your entire system on finding food in the environment.” In fact, some biologists believe that human intelligence itself evolved because it made early hominids more effective hunters, gathers and foragers.

Horvath says we can use the hormonal discoveries to our cognitive advantage. Facing the LSAT, a final exam or a half-day job interview? Go in mildly hungry, not carbo-loaded for endurance, and snack to maintain that edgy state. Such advice, applied on a national scale, might help save our schools. Since overweight kids have suppressed ghrelin levels, Horvath theorizes that perhaps the obesity epidemic has contributed to declining test scores and other American educational woes.

Orginal Link

1. Start early

2. Use your 401k(US) CPF(SG)

3. Keep it simple

4. Don't try to beat the market

5. Don't chase trends

6. Make saving automatic

7. Go heavy on stocks

8. Hold down fees

9. Ditch credit card debt

10. Defer taxes

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1. Paper currency.

2. Row crops.

3. Deep drilling for gas.

4. Firworks.

5. Gun powder.

6. Flame Thrower.

7. Parachute.

8. Rudder.

9. The wheelbarrow.

10. Compass.

1. Only run what you need.

2. Kill extraneous process.

3. Be gentle.

4. Adjust your screen brightness.

5. Disable built-in hardware features you don't need.

6. Be careful with the external peripherals too.

7. Use power saving features carefully.

8. Monitor operating temperature.

9. Maintain the condition of your battery.

10. Plug your laptop into the AC adapter.

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10. Beer

9. Anger

8. Coffee

7. LSD

6. Sunlight

5. Maggots

4. Marijuana

3. Red Wine

2. Chocolate

1. Sex

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It's not always up to the man to make things exciting. Sometimes the woman should take things into their own hands. Many women fail at doing so because they are either too shy or too lazy to do the little things that matter to a man. Here is a list of the top things women usually suck (no pun intended) at in bed.

1. Not moving

2. Kissing other parts of our body

3. Taking control

4. Keeping it new

5. Communicating pleasure

6. Paying attention to our pleasure

7. Cleaning up immediately after sex

8. Cleaning your body immediately after sex

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